18/12/14

What is gout?


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Gout is a form of arthritis caused the most pain. Gout occurs when too much uric acid builds up in the body. The accumulation of uric acid can lead to:
  • The sharp uric acid crystals deposited in the joints, often in the big toe
  • The layer deposition of uric acid (urate hotel called) look like lumps under the skin
  • Kidney stones from uric acid crystals in the kidneys. 
 
For many people, the first attack by gout occurs in the big toe. Typically, the pain it causes a sleeping person to wake up. Toes are soreness, redness, warmth and swelling.
Gout can cause:
  • Pain
  • Swelling
  • Redness
  • Hot
  • Stiffness.
In addition to the big toe, gout can affect:
  • Instep
  • Ankle
  • Heel
  • Knee
  • Wrist
  • Finger
  • Elbow.
The pain caused by gout can be caused by stressful events, alcohol or drugs or other diseases. The initial pain is usually relieved within 3 to 10 days, even without treatment. The next attack may not occur for months or even years.

The cause of gout?

Gout is caused by the accumulation of too much uric acid in the body caused. Uric acid is produced from the breakdown of substances called purines. Purines found in all tissues of the body. These compounds also found in many foods, such as liver, beans, and dry peas and anchovies.
Normally, uric acid dissolves in the blood. It is excreted through the kidneys and out of the body in urine. However, uric acid can build up in the blood when:
  • Increasing the amount of uric acid the body makes.
  • The kidneys do not excrete uric acid out.
  • Eating too many foods rich in purines.
When the concentration of uric acid in the blood, which is known to increase blood uric acid. Most people do not increase blood uric acid causes gout. But if there is too much uric acid crystals forming in the body, it can cause gout.
You are more likely to develop gout than if:
  • Having family members with the disease
  • As men
  • Overweight
  • Drinking too much alcohol
  • Eating too many foods high in purines
  • There are defects in the enzyme causes the body Persistent purine
  • Being in environmental lead exposure
  • Had organ transplants
  • Use of certain medications such as diuretics, aspirin, cyclosporine or levodopa
  • Use of vitamin niacin.

Gout Symptoms and Diagnosis How is?

The doctor will ask about symptoms, medical history and your family history of gout. The signs and symptoms of gout include:
  • Increased blood uric acid (uric acid levels in the blood)
  • Uric acid crystals in the joint fluid
  • Many arthritis pain due to acute
  • Arthritis developed in one day, lead to joint swelling, redness and heat up
  • The pain caused by arthritis in only one joint, usually the toe, ankle or knee.
To confirm the diagnosis of gout, your doctor may take a sample of fluid from the inflamed joint to look for crystals related to gout.

Treatment of Gout How?

Doctors use pharmaceuticals to treat acute pain caused by gout, including:
  • Non-steroidal anti-inflammatory drug (NSAID)
  • Corticosteroids (steroids secreted by the adrenal cortex), such as prednisone
  • Conchixin, works best when used within the first 12 hours of acute pain.
Sometimes doctors prescribe NSAIDs or conchixin in small daily doses to prevent future attacks. There are also drugs that help reduce uric acid levels in the blood.

People with gout Can Do to Stay Healthy?

Some things you can do to stay healthy are:
  • Use of prescription drugs as directed.
  • Tell your doctor about all the medicines and vitamins you use.
  • Planning for the monitoring visit with your doctor.
  • Maintaining a healthy diet and balanced. Avoid foods rich in purines and drink plenty of water.
  • Exercise regularly and maintain a healthy body weight. Ask your doctor about how to lose weight safely. Lose weight fast or too much can increase uric acid levels in the blood.

Studies are being conducted on Gout Symptoms?

 
Scientists are studying:
  • The type of NSAID therapy does most effective gout
  • Optimal pharmaceutical dosage for gout
  • The new drugs to reduce uric acid in the blood and reduce symptoms safely
  • New therapies to prevent chemical called tumor necrosis factor
  • The enzymatic decomposition of purines in the body
  • The role of food and some vitamins
  • The role of genetic factors and environmental
  • The interaction between cells related to acute pain caused by gout.
Scientists are also studying the role of genetic factors in the work environment and increased blood uric acid and gout.

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