Why Gout growing

  Gout was discovered from ancient times. Today, gout is more concerned by the increase of the disease. Food and genetic factors play a role in the pathogenesis of primary gout . Increase the risk of heart disease and changes in the treatment of gout.

Gout has been known since long. Percentage of gout is increasing in both the US and European countries and many other countries such as Japan, China and New Zealand. Percentage of gout in the UK and Germany in 2000 - 2005 was 1.4% and in the US in 1996 was 0.94%. The proportion of the population of gout in 5 major cities in western China accounted for 1.14%. China is a country with a developing economy, gout here are related to obesity, hypertension, consumption of meat, fish and wine.

In our country, nowadays very common disease in the joints and base clinic treating osteoarthritis. All year round, we are experiencing gout patients in the hospital. In patients with chronic gout illness is severe: the deformed joints, movement very difficult, painful joints due to acute inflammation of multiple joints, decreased quality of life, treatment costs due to expensive treatment the comorbid conditions such as dyslipidemia, hypertension, diabetes, joint infection, kidney failure, pancreatitis ...

The frequency of gout-related increase by an average lifespan increases, changes in diet and an increase in hypertension. Many studies have shown an association between hypertension and increased blood uric acid levels and increased risk of myocardial infarction in patients with gout, especially using high concentrations alcool. Increased risk of coronary heart disease in people with gout. Eswar Krishnan study on 12,866 men followed for 6.5 years 118 patients with acute myocardial infarction in patients with gout group (10.5%) and 990 patients with acute myocardial infarction in the group not gout (8.43%), the authors found in patients with gout risk acute myocardial infarction than those who did not have gout. Gout to be greater when the combination of cardiovascular disease and mortality risk is very high. In the mountains, the summer heat loss through sweating skin reduces diuresis, patients with gout is unfavorable factors. Uric Acid Kidney mainly through road and a small amount through the digestive tract. Winter, mountain high temperatures too low, demand is rising spirits factors that increase uric acid synthesis. Therefore, in patients with gout mountainous always prevent gout attacks and complications of cardiovascular disease associated.

Most patients with gout uric acid concentration> 416.5 mmol / l. Recommendation of the European School rheumatism (EULAR) aim to achieve reduction of uric acid in the treatment of <360 mmol / l. Increased blood uric acid is influenced by genetic factors and food. Research in China also shows that men consume more soft drinks (soda) leads to a very high risk of gout. Hyperinsulinemia reduces urinary urate excretion and lead to increased uric acid. Use of purine-rich foods, spirits led to increased urate production and increased uric acid synthesis.

Treatment of gout should pay attention to the treatment of coordination. Hypertension should stop using diuretics and losartan to treat hypertension. Patients with hyperlipidemia should have a reasonable diet, including the use of drugs or atorvastatin group fenofibrat. Patients with diabetes may reduce blood insulin secretion, reduce uric acid and stop smoking.